General Information

  • ID:  hor001344
  • Uniprot ID:  E9HJY4
  • Protein name:  SIFamide
  • Gene name:  NA
  • Organism:  Daphnia pulex (Water flea)
  • Family:  FMRFamide related peptide family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Daphnia (genus), Daphniidae (family), Anomopoda (infraorder), Cladocera (suborder), Diplostraca (order), Phyllopoda (subclass), Branchiopoda (class), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  TRKLPFNGSIF
  • Length:  11
  • Propeptide:  MRSSFIVVMVCVVVVLTFWGQVAEATRKLPFNGSIFGKRSNQGTDKLESPSNLQLLCDAAMNACSDWLPIGSK
  • Signal peptide:  MRSSFIVVMVCVVVVLTFWGQVAEA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-E9HJY4-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor001344_AF2.pdbhor001344_ESM.pdb

Physical Information

Mass: 145804 Formula: C60H94N16O15
Absent amino acids: ACDEHMQVWY Common amino acids: F
pI: 11.65 Basic residues: 2
Polar residues: 4 Hydrophobic residues: 4
Hydrophobicity: -13.64 Boman Index: -1634
Half-Life: 7.2 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 70.91
Instability Index: 2272.73 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  21830762
  • Title:  Genomics, Transcriptomics, and Peptidomics of Daphnia Pulex Neuropeptides and Protein Hormones